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7-hydroxymitragynine is one of the primary alkaloids that give kratom its powerful painkilling effects. Find out how it works and what it can do for you.

Cloniprazepam is a prodrug of clonazepam that is under study for treating anxiety disorders and other mental health conditions.

Camazepam is a psychoactive benzodiazepine used to treat anxiety, panic disorders, and seizures. Here’s everything you need to know about using camazepam safely.

Alpha,N-DMT or α,N-DMT is a DMT analog created by Alexander Shuglin with few psychedelic effects and a possible MAOI.

DMT

Sassafras is often sold as MDA, but the sassafras tree has generations of use like making rootbeer and medicine — along with potential psychoactive effects.

The traditional process for making ayahuasca can take several hours and requires plants only found in the Amazon forest — but there are other methods.

It’s not just people that enjoy getting high. Several species of animals enjoy some of the mind-altering psychoactive fruits of nature as well.

Alzheimer’s destroys, and there isn’t much we can do about it. Could psychedelics move us one step closer to overcoming AD and other neurodegenerative disorders?

Since ancient times, shamans in Mexico have used the LSA containing seeds of the morning glory vine for healing and divination — psychedelic pharmacopeia.