Category: Tryptamines
The most common class of psychedelic substances is tryptamine psychedelics.
The most famous members of this class include DMT, psilocybin, and LSD.
These compounds interact with the serotonergic system (primarily the 5-HT2A receptor) to produce shifts in perception, ego-death, and introspection.
Alexander Shulgin outlined dozens of natural and synthetic tryptamine-based psychedelics in one of his books titled TiHKAL (Tryptamines I Have Known and Loved).
Ayahuasca is a traditional entheogenic formula made from two Amazonia plant species — one containing DMT, the other an MAO inhibitor.
DMT is a powerful psychoactive compound found in ayahuasca, bufo toads, and a pure crystalline form called 5-MeO-DMT.
