Category: Synthetic Psychedelics

Psychedelics can be either natural or synthetic. Many (but not all) synthetic psychedelics were inspired or based on natural compounds.

For example, the largest class of synthetic psychedelics is the phenethylamine class, which is based on the structure of mescaline (the active ingredient in San Pedro or Peyote cactus).

Another famous synthetic psychedelic is LSD — which was a chemically-altered version of ergotamine from the ergot fungus.

Substances are tweaked and adapted in a lab to slightly alter their chemical structure — producing an entirely new compound.

There are thousands of synthetic psychedelics in the world today — largely created in response to the efforts of the drug war to ban psychoactive substances. Most of them are considered research chemicals because they lack sufficient scientific research to elucidate their mechanism of action or short/long-term safety profiles.

Naturally-occurring psychedelics can also be made synthetically, such as 5-MeO-DMT which is found naturally in the Colorado River Toad.

Arylcyclohexylamines are a class of hallucinogenic substances that produce feelings of dissociation & depersonalization. Learn about PCP, ketamine, & more.

DOM is one of the many creations of the late Alexander Shulgin. Learn why DOM is considered one of his favorite psychedelic creations of all time.

Benzodiazepines are a large class of psychoactive drugs used for their hypnotic & anxiolytic effects. There are over 2000 benzos (BZD & DBZD) in existence today.

The 2C psychedelic family boasts a long list of compounds, each with a distinct set of effects. Popular members of the group include 2C-B, 2C-C, 2C-D, 2C-E, & 2C-I.

LSD (AKA “Acid”) is just one of many members of the lysergamide family of psychedelics — a few of which possess even stronger psychedelic effects.

PCP (phencyclidine), also known as angel dust, is a powerful dissociative psychedelic with stimulant, euphoric, & deliriant effects.

2C-T is the first of a series of psychedelics in the subfamily 2C-T-X. This compound is psychoactive but has mild effects compared to 2C-T-2 or 2C-T-7.

2C-T-7 is a mixed bag. Some users suggest it's one of the greatest psychedelics of all time; others compare it to the deliriant effects of datura of DPH.

2C-T-2 is a member of the 2C-X family. It’s described as a middle-ground between MDMA & LSD. Some experts are interested in using this with psychedelic therapy.