Category: Tryptamines

The most common class of psychedelic substances is tryptamine psychedelics.

The most famous members of this class include DMT, psilocybin, and LSD.

These compounds interact with the serotonergic system (primarily the 5-HT2A receptor) to produce shifts in perception, ego-death, and introspection.

Alexander Shulgin outlined dozens of natural and synthetic tryptamine-based psychedelics in one of his books titled TiHKAL (Tryptamines I Have Known and Loved).

Magic mushrooms and LSD have a lot in common, but some key differences exist. Here's a quick breakdown of their distinctions and commonalities.

Ololiúqui is the Aztec name for the psychedelic LSA containing seeds of the morning glory plant used in ancient rituals and medicine.

Since ancient times, shamans in Mexico have used the LSA containing seeds of the morning glory vine for healing and divination — psychedelic pharmacopeia.

Liquid LSD is a synthetic hallucinogenic drug made up of LSD crystals dissolved in a solution and taken on a sugar cube or soaked into acid blotter tabs.

Dolphins, LSD, extraterrestrials, and sensory deprivation tanks were the main topics of conversation within a small research lab on an island in the 60s.

DiPT or N,N-Diisopropyltryptamine, is a tryptamine that triggers auditory distortions. A DMT analog discovered by Sasha Shulgin, DiPT, could help study hearing.

5-MeO-DMT is a powerful psychedelic, often creating an experience of ineffable oneness. It comes from plants, a toad, and thousands of years of indigenous use.

1B-LSD is a lysergamide and analog for LSD. As a potential prodrug, 1B-LSD — and related compounds like 1P-LSD — convert to LSD through digestion.

Microdosing psychedelics like LSD can benefit creativity and enhance problem-solving skills, but could it also improve a good night's sleep?