2-FDCK: A Popular Ketamine Alternative [Caution Advised]

By Enrique Santos Last Updated: June 19, 2023
Last Updated: June 19, 2023

2-FDCK was first synthesized in 2013 in an attempt to create and evaluate new anesthetic drugs based on ketamine. From there, it wasn’t long before it started appearing in several European countries as a ‘new psychoactive substance’ (NSP).

Chemically, 2-FDCK is classified as an arylcyclohexylamine and is the fluoro-substituted analog of ketamine.

There is virtually no peer-reviewed information on the effects profile of this dissociative psychedelic.

However, there are an increasing number of anecdotal reports of this substance appearing online as more people manage to get their hands on it.

2-FDCK (2-Fluorodeschloroketamine) Specs

Chemical Name2-Fl-2′-Oxo-PCM
Level of RiskModerate to High
Other Names2-Fluroketamine, Fluoroketamine, and 2-FK
Most Common Side EffectsPsychosis, Seizures, Anxiety, Paranoia, Agitation, Confusion. Increased heart rate and blood pressure, Palpitations, Chest pain, and Difficulty breathing.
Duration of EffectsOne to three hours
Estimated Threshold DoseUnknown
Common DoseUnknown
Legality/StatusResearch Chemical
PubChem ID:13771618

Tripsitter Safe 2-FDCK Guidelines:

  • 🐍 I understand why arylcyclohexylamines should be treated with respect
  • ⚖️ I’m familiar with the laws for arylcyclohexylamine class in my country & state
  • 🍄 I’m familiar with and confident in the dose I’m taking
  • 🧪 I’ve tested a sample of the substance I’m using with a drug-testing kit
  • 💊 I’m not mixing any medications or other substances with 2-FDCK
  • 🏔 I’m in a safe & comfortable environment with people I trust
  • 🐺 One of the members of my group is responsible and sober (AKA a trip sitter)
  • ⏳ I have nothing important scheduled for after the trip
  • 🧠 I’m in a sound & healthy state of mind
  • ❤️ I don’t have any underlying health issues — don’t take  2-FDCK if you have underlying heart, neurological, or psychiatric disorders
  • 👭 Use the buddy system —  2-FDCK can remove your inhibition and allow you to make unsafe decisions, always stay with people you trust, and never go out alone

What Are The Effects of 2-FDCK (2-Fluorodeschloroketamine)?

The effects of 2-FDCK are, unsurprisingly, reported as being quite similar to those of its parent compound, ketamine [1]. Although scientific, peer-reviewed studies are not available, there is a wealth of user-generated information that draws us to this conclusion.

Sites like Psychonaut and forums like Bluelight are places where the designer drug community congregates online in order to share their experiences with a host of different substances. This method is obviously lacking in scientific objectivity but is, in fact, quite adept at sketching out the subtle differences in the subjective effects of similar compounds.

Here are the subjective effects related to the use of 2-FDCK:

  • Physical effects — Pain relief, Spontaneous physical sensations, Physical euphoria, Dizziness, Motor control loss, Nausea, Perception of bodily lightness, Physical autonomy, Spatial disorientation, Tactile suppression, Orgasm suppression
  • Visual effects — Double vision, Frame rate suppression, Pattern recognition suppression, Visual acuity suppression, Distortions, Environmental cubism, Environmental orbism, Perspective distortions, Scenery slicing, Geometry, Hallucinatory states, Internal hallucination
  • Cognitive effects — Anxiety suppression, Compulsive redosing, Conceptual thinking, Creativity enhancement, Déjà vu, Depersonalization, Derealization, Disinhibition, Dream potentiation, Cognitive euphoria, Immersion enhancement, Analysis suppression, Introspection, Memory suppression, Ego death, Amnesia, Time distortion, Thought deceleration, Increased music appreciation

The cognitive impacts of 2-FDCK are quite similar to those of ketamine, and some individuals may not be able to distinguish between them.

However, subjectively, the effects of 2-FDCK usually occur at a slower pace and include unique psychedelic effects that are slightly different from ketamine.

Some users also claim that higher dosages of 2-FDCK can result in more confusion and greater difficulty achieving a “hole” compared to ketamine, while others do not seem to notice this and find the experience to be just as enjoyable. Despite any differences, 2-FDCK is thought to have the same antidepressant effects as ketamine.

It should also be noted that 2F-DCK’s effects are highly dose-dependent, with lower doses producing alcohol-like intoxication and higher doses producing hallucinogenic out-of-body states (also known as a “k-hole“).


  1. Li, F., Du, H., Wu, B., Wei, J., Qiao, Y., Lai, M., … & Di, B. (2022). 2-Fluorodeschloroketamine has similar abuse potential as ketamine. Addiction Biology, 27(3), e13171.